Study To Evaluate Karxt For Treating Manic Episodes In Bipolar-I Disorder
Posted Date: May 19, 2025
- Investigator: Caleb Adler
- Specialties: Bipolar Disorder, Psychiatry/Psychology
- Type of Study: Drug
KarXT is a novel combined formulation of two drugs, xanomeline tartrate and trospium chloride. KarXT has the potential to provide a novel mechanism of action for the treatment of bipolar mania. Most antimanic agents approved in this century have the same or similar mechanisms of action, perpetuating similar side effect profiles. This is an inpatient study, the goal of which is to demonstrate the efficacy of KarXT in BP-I mania or mania with mixed features while exploring the side effect profile.
Criteria:
Adults With A Bipolar Manic Or Mixed Episode, Who Might Benefit From An Investigational Medication.
Keywords:
Bipolar Disorder, Cobenfy, Mania
For More Information:
Karen Tugrul
513-558-6831
tugrulkc@ucmail.uc.edu