Thymus Cancer

Thymus cancer is a cancer that affects the thymus, a small organ located in front of the lungs and behind the breastbone (sternum). The thymus is responsible for creating white blood cells, which are the body’s defense against infection.

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About This Condition

Understanding Thymus Cancer

What is thymus cancer?

Cancer is made of changed cells that grow out of control. The changed (abnormal) cells often grow to form a lump or mass called a tumor. Cancer cells can also grow into (invade) nearby areas. And they can spread to other parts of the body. This is called metastasis.

The thymus is a small organ in the front part of your chest under the top part of the breastbone. The thymus makes white blood cells called lymphocytes. It’s an important part of your immune system.

Thymus cancer is a rare cancer that starts in the cells that make up the thymus. There are two main types of thymus tumors:

  • Thymoma. This is more common. It’s slow growing but can grow into nearby organs or spread to other parts of your body.

Thymic carcinoma. This tumor grows more quickly. It has often spread to other parts of the body by the time it’s found.

Who is at risk for thymus cancer?

A risk factor is anything that may increase your chance of having a disease. The exact cause of someone’s cancer may not be known. But risk factors can make it more likely for a person to have cancer. Some risk factors may not be in your control. But others may be things you can change.

Thymus cancer is rare, but anyone can get it. Only a few factors are known to increase risk for thymus cancer, and they aren’t under your control. The risk factors are:

  • Older age.

  • Being Asian American or a Pacific Islander.

Thymus cancer doesn’t seem to be linked to family history. This means the risk isn’t inherited from your parents. No environmental or lifestyle factors are known to increase thymus cancer risk.

Can thymus cancer be prevented?

There is no known way to prevent thymus cancer.

Are there screening tests for thymus cancer?

There are no regular screening tests for thymus cancer. Screening tests are done to check for disease in people who don’t have symptoms.

What are the symptoms of thymus cancer?

Thymus cancer may not cause symptoms unless the tumor grows large enough to press on nearby organs or blood vessels in your chest. If this happens, symptoms can include:

  • A cough that doesn’t go away or gets worse over time.

  • Chest pain.

  • Shortness of breath.

  • Trouble swallowing.

  • Loss of appetite.

  • Unexplained weight loss.

  • Tiredness.

  • Weakness.

  • Swelling in your face and arms.

  • Lightheadedness or dizziness.

  • Headaches.

Some people with a thymus tumor also develop an autoimmune disease, most often myasthenia gravis. This may be the first sign of thymus cancer.

Many of these symptoms may be caused by other health problems. It’s important to see your healthcare provider if you have these symptoms. Only a healthcare provider can tell if you have cancer.

How is thymus cancer diagnosed?

Sometimes a thymus tumor is found by an imaging test of the chest that’s done for another reason. If your healthcare provider thinks you may have thymus cancer, they will ask you about your health history, symptoms, risk factors, and family history of disease. A physical exam will be done. You may also have one or more of these tests:

  • Chest X-ray.

  • CT scan.

  • Blood tests.

Unlike many other types of cancer, a biopsy isn’t always needed to diagnose thymus cancer before surgery. This is because imaging tests can often show that cancer is most likely present. A diagnosis of thymus cancer is then confirmed at the time of surgery. At that time, the surgeon removes the tumor and sends it to a lab. In the lab, a pathologist looks at the removed tissues to check for cancer cells.

After a diagnosis of thymus cancer, you’ll likely have other tests. These help your healthcare providers learn more about your cancer. They can help determine the stage of the cancer. The stage is how much and how far the cancer has spread (metastasized) in your body. It is one of the most important things to know when deciding how to treat the cancer.

Once your cancer is staged, your healthcare provider will talk with you about what the stage means for your treatment. Be sure to ask your healthcare provider to explain the stage of your cancer to you in a way you can understand.

How is thymus cancer treated?

Your treatment choices depend on the type of thymus cancer you have, test results, and the stage of the cancer. The goal of treatment may be to cure you, control the cancer, or to help ease problems caused by cancer. Talk with your healthcare team about your treatment choices, and what the risks and side effects may be.

Types of treatment for cancer are either local or systemic. Local treatments remove, destroy, or control cancer cells in one area. Surgery and radiation are local treatments. Systemic treatment is used to destroy or control cancer cells that may have traveled around your body. When taken by pill or injection, chemotherapy is a systemic treatment. You may have one treatment or a combination of treatments.

Thymus cancer may be treated with:

  • Surgery.

  • Radiation therapy.

  • Chemotherapy (chemo).

Talk with your healthcare providers about your treatment options. Make a list of questions. Think about the benefits and possible side effects of each option. Talk about your concerns with your healthcare provider before making a decision.

What are the side effects of treatment?

Cancer treatment such as chemotherapy and radiation can damage normal cells. This can cause side effects such as hair loss, mouth sores, and vomiting.

Talk with your healthcare provider about side effects you might have and ways to manage them. There may be things you can do and medicines you can take to help prevent or control side effects.

Coping with thymus cancer

Many people feel worried, depressed, and stressed when dealing with cancer. Getting treatment for cancer can be hard on your mind and body. Keep talking with your healthcare team about any problems or concerns you may have. Work together to ease the effects of cancer and its symptoms on your daily life.

Here are tips:

  • Talk with your family or friends.

  • Ask your healthcare team or social worker for help.

  • Speak with a counselor.

  • Talk with a spiritual advisor, such as a minister or rabbi.

  • Ask your healthcare team about medicines for depression or anxiety.

  • Keep socially active.

  • Join a cancer support group.

Cancer treatment is also hard on the body. To help yourself stay healthier, try to:

  • Eat a healthy diet, with a focus on high-protein foods.

  • Drink plenty of water, fruit juices, and other liquids.

  • Keep physically active.

  • Rest as much as needed.

  • Talk with your healthcare team about ways to manage treatment side effects.

  • Take your medicines as directed by your team.

When should I call my healthcare provider?

Your healthcare provider will talk with you about when to call. You may be told to call if you have any of the below:

  • New symptoms or symptoms that get worse.

  • Signs of an infection, such as a fever.

  • Side effects of treatment that affect your daily function or don’t get better with treatment.

Ask your healthcare provider what signs to watch for and when to call. Know how to get help after office hours and on weekends and holidays.

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