Normal Pressure Hydrocephalus

Normal pressure hydrocephalus (NPH) is a brain disorder in which the chambers called ventricles in the brain are overfilled with cerebrospinal fluid because of overproduction in the body. This overproduction can be caused by a variety of factors.

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Understanding Normal Pressure Hydrocephalus

What is normal pressure hydrocephalus?

The brain has chambers called ventricles that normally contain fluid. This fluid is called cerebrospinal fluid (CSF). It cushions the brain and spinal cord. Normally your body makes just enough CSF each day and absorbs that same amount. Sometimes, though, too much fluid can build up in the ventricles. This can lead to a normal pressure hydrocephalus (NPH).

What causes normal pressure hydrocephalus?

The cause of excess fluid in the ventricles of the brain may be due to injury, bleeding, infection, brain tumor, or surgery on the brain. But the cause is often not known. When excess fluid builds up in the ventricles, they enlarge and press against nearby brain tissue. This extra fluid and pressure can lead to brain damage.

NPH is rare. It most often affects older adults, and its symptoms can be like those of Alzheimer's and Parkinson's diseases. A healthcare provider familiar with these conditions can often tell the difference between these diseases and NPH after a clinical evaluation and sometimes special testing.

Who is at risk for normal pressure hydrocephalus?

You are at increased risk for NPH if you:

  • Are older than age 60.

  • Have a brain infection.

  • Have had a head injury.

  • Have a brain tumor.

  • Have undergone brain surgery.

What are the symptoms of normal pressure hydrocephalus?

These are possible symptoms of NPH:

  • Trouble walking (feels like the feet are stuck to the ground).

  • Poor balance.

  • Falling.

  • Changes in the way you walk.

  • Forgetfulness and confusion.

  • Mood changes.

  • Depression.

  • Difficulty responding to questions.

  • Loss of bladder control.

How is normal pressure hydrocephalus diagnosed?

Your medical team may need to do a number of tests to confirm NPH, such as:

  • Physical exam and review of your symptoms.

  • Evaluation of the way you walk.

  • CT or MRI scans of your brain.

  • Spinal tap to remove a sample of your CSF.

  • A temporary drain put in place to see if prolonged spinal fluid drainage helps symptoms.

How is normal pressure hydrocephalus treated?

A commonly used treatment for NPH is surgery to place a tube, called a shunt, into the brain to drain the excess fluid. The shunt is usually inserted into a ventricle in the brain and then passed under your skin from your head through your neck and chest to your abdomen. The extra fluid in your brain flows through the shunt into your abdomen, where your body absorbs it. The ventricles in your brain may then go back to their normal size. The shunt stays in place as long as there is too much CSF in the brain.

Implanting a shunt doesn’t work for everyone, but some people do benefit from it. Getting prompt diagnosis and treatment helps improve your chances of a good outcome.

What are the possible complications of normal pressure hydrocephalus?

The complications of NPH include:

  • Difficulty walking.

  • Trouble thinking.

  • Loss of bladder control.

When should I call my healthcare provider?

If you or an older relative have changes in walking, thinking, mood, or loss of bladder control, contact your healthcare provider. Describe when the changes started and how they are affecting your physical activity and emotional well-being.

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