Entbi
Posted Date: Oct 25, 2025
- Investigator: Ishita Basu
- Specialties: Neurosurgery, Neurotrauma
- Type of Study: Device
The primary objectives of this study are 1) to determine neural biomarkers of cognitive functional recovery in TBI and 2) to investigate the neuromodulatory effects of A-tES on target neural oscillations, cognitive functions, and quality of life (QOL) measures in the acute and sub-acute/chronic phases of TBI.
Criteria:
Inclusion Criteria: (1) Moderate To Severe Tbi Which Defined As The Glasgow Coma Scale (Gsc) In The 3-12 Range And Greater Than 30 Min Of Loss Of Consciousness And/Or A Post-Traumatic Amnesia That Lasts More Than 24 Hours And/Or An Alteration Of Mental State Over 24 Hours, (2) Age 18-80 Years, (3) Isolated Tbi And (4) Intelligible Speech And Galveston Orientation And Amnesia Test (Goat) Score >70 At Time Of Enrollment. Exclusion Criteria: (1) Persistent Bilateral Non-Reactive Pupils Or Other Evidence Of Non-Survivable Injury, (2) Decompressive Craniectomy To Treat Refractory Icp Subsequent To Diffuse Injury, (3) Co-Enrollment In Another Therapeutic Tbi Trial, (4) Pregnancy And (5) Patients With Polytrauma. Enrollment May Occur At Any Time After Eligibility Screening And Informed Consent.
Keywords:
Tbi, Acute
For More Information:
Alexandra Ramirez
NULL
ramiream@ucmail.uc.edu