Clinical Study

Propofol And Difficult Sedation - Retrospective Study

Posted Date: Jun 24, 2022

  • Investigator: Michael Grau
  • Specialties: ADD/ADHD, Adolescent Psychiatry/Psychology, Psychiatry/Psychology
  • Type of Study: Observational/Survey

Objective of this study is to retrospective cohort study to compare the amount of Propofol (mg/kg/min) used during dentoalveolar procedures under IV sedation in healthy patients and patients with diagnosed mental disorders such as anxiety and depression with or without medications. In training, it has been taught that patients with certain history such as mental disorders are difficult to sedate during standard IVS for dentoalveolar procedures. But most accounts were anecdotal and currently there are no in-depth studies related to this topic in the field of oral and maxillofacial surgery. This study should provide objective evidence whether diagnosed mental disorders have associations with difficult IV sedation.


Potential Participants Will Initially Be Identified By Searching Through University Of Cincinnati’S Oral And Maxillofacial Procedure Log Of All Patients Who Underwent An Open Reduction And Internal Fixation (Orif) Of A Mandible Fracture Within The Defined Timeframe In 2018.


Psychiatric Illness, Anesthetic Techniques

For More Information:

Reese Triana

  • This contact page is monitored Monday – Friday during business hours, 8 am to 5 pm EST. Do not rely on communication through this website for medical treatment or care. This website is not designed for such purposes.
    For questions regarding clinical studies at UC Health, contact us at or (513) 245-3417.