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COVID-19 Vaccine

The COVID-19 vaccine is safe and effective.

Since March 2020, COVID-19 has touched every part of our lives. We’ve been challenged like never before. At UC Health, it is our responsibility to provide a source of hope to our region. And now, we have a new reason for hope. As vaccination efforts reach our community, we are ready to begin putting this pandemic behind us.

Getting The Vaccine

When and how to get your COVID-19 vaccine.

UC Health is following the phased distribution plan set by the State of Ohio. We are now vaccinating community members as part of Phase 1B. We will release more information about future phases when it becomes available.

Please check back often as we will continue to provide updates as each new phase is announced.


Clinical trials ensure a vaccine is safe and effective. Vaccines must go through rigorous research before they can be approved by the FDA. In ongoing COVID-19 vaccine studies, tens of thousands of volunteers participated, and scientists closely studied every volunteer for side effects and efficacy.

Jarelle Marshall recieving the COVID-19 vaccine

What is Emergency Use Authorization (EUA)?

The FDA can issue an Emergency Use Authorization (EUA) when a public health threat demands a timely solution. The FDA reviews available data and decides whether known and potential benefits outweigh known and potential risks. An EUA requires regular safety standards are met in clinical trials.

Approved Vaccines

COVID-19 Vaccine Dosage timeline for Moderna vs. Phizer

The COVID-19 vaccine is safe and effective.

The mRNA vaccines from manufacturers Pfizer and Moderna have been shown in controlled clinical trials to be about 95% effective in preventing COVID-19. Two doses are required for each.

About mRNA Vaccines

The vaccine is new. But the science isn’t. Scientists have been developing this technology for decades in the hopes that it would be the future of medicine. When the pandemic began, all that was needed to create a COVID-19 vaccine was its genome — the genetic code – which scientists shared in January 2020.

Most vaccines work by taking specific pieces (proteins) of a virus and injecting them into the body. Some vaccines work by introducing a weakened or inactive strain of a virus into the body. The body recognizes the foreign protein or “attenuated” virus and triggers an immune response, creating antibodies that protect against disease. If a vaccinated person becomes infected, the body already has a defense mechanism to prevent illness.

mRNA, or messenger ribonucleic acid, is a molecule similar to DNA that sends messages to cells to make proteins. DNA is the genetic blueprint that tells cells what to do. mRNA is like a machine taking direction on what to build (such as proteins). The COVID-19 mRNA vaccine does not contain the coronavirus. Instead, it sends a message to the cells to create a protein that looks like a piece of the surface of coronavirus. The body recognizes the foreign protein, sometimes called an antigen, and creates antibodies that protect against COVID-19. After the mRNA sends its message, it is destroyed by the cell within a couple of weeks.

The COVID-19 vaccine is the first mRNA vaccine approved for use in the United States.

It’s important to understand that scientists have been developing this technology for decades in the hopes that it would be the future of medicine. When the pandemic began, all that was needed to create a COVID-19 vaccine was its genome — the genetic code, which scientists shared in January 2020. 

The vaccine is designed to trigger an immune reaction in your body. It is normal for the body to increase temperature (fever), or to activate cells, or send out signals to fight off germs. These responses are the body’s way of defending itself, and they can cause you to feel uncomfortable and sick. Therefore, you may experience mild flu-like symptoms, most commonly fatigue, headache, fever and muscle aches. You may also experience some soreness at the site of the injection. Most side effects are minor and typically go away within a few days. Less than 10% of people in the COVID-19 vaccine studies needed to take any medicines like acetaminophen (Tylenol) or ibuprofen (Motrin) to treat these symptoms. And when they did, it was typically for just a day or so.

You cannot get COVID-19 from the vaccine.

There are no known long-term effects of the vaccine beyond a week after receiving it. The science suggests there are not likely to be longer-term side effects, but we need more time to completely confirm this. 

Frequently Asked Questions about the COVID-19 Vaccine

Frequently Asked Questions

We know you have a lot of questions about this vaccine and about your health, and we are committed to answering them as we learn more. 

COVID-19 Vaccine News



Where Can I Find More Information?

For the latest information on the COVID-19 vaccine, you can also visit or your state or local health department for the latest details.

Contact Us

At UC Health, we lead the region in scientific discoveries and embrace a spirit of purpose – offering our patients and their families something beyond everyday healthcare. At UC Health, we offer hope.